Throughout this study we have a recurring right hand pattern which repeats throughout the majority of the piece. Once we have this pattern under our fingers we can concentrate on negotiating the chord changes as smoothly as we possibly can.
I like to think of the right hand pattern in two ways: Ascending we have four groups of two notes each which is separated by a string in between i.e. we are skipping a string. Descending we have four groups of two strings this time played on adjacent strings. It sounds like a lot but is actually quite simple and it helps me to negotiate the pattern easier especially at high speeds.
Be sure that you do not add any unnecessary accenting as it is quite a common problem especially amongst guitarists who are new to Hybrid picking technique. Always aim for absolute clarity and consistency in volume and tone.